Nov 24, 2009
Seminar on Bio-Artificial Liver
The liver is the largest gland in our body and performs a variety of tasks that impact all parts of the body, a spongy mass of wedge-shaped lobes that has many metabolic and secretory functions. The liver secretes bile, a digestive fluid; metabolizes proteins, carbohydrates, and fats; stores glycogen, vitamins, and other substances; synthesizes blood-clotting factors; removes wastes and toxic matter from the blood. You can also Subscribe to FINAL YEAR PROJECT'S by Email for more such projects and seminar.
As a result, liver disease has widespread effects on virtually all other organ systems. The only treatment available for liver failure is liver transplant surgery; but donor organs are difficult to obtain, and the procedure, which is complex and expensive, is frequently unsuccessful.
The bio-artificial liver device is intended to provide temporary support to patients with liver failure until their liver recovers spontaneously or until transplantation is possible. The device is connected to a vein and remains outside their body.
It should help remove toxins from the patient’s own liver cells, as the patient’s blood circulates in a chamber with pig liver cells inside polymer and synthetic membranes. The membranes allow toxins to pass through, but prevent proteins, and other cell byproducts from the pig cells to get into the patient’s blood.
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